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KMID : 1123920050190041011
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Korean Journal of Oriental Physiology and Pathology
2005 Volume.19 No. 4 p.1011 ~ p.1015
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Antitumor and Anti-metastatic Effect of Mineral Powder
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Song Gyu-Yong
Bae Ki-Whan
Myung Chang-Seon
Jin Wen-Yi
Park Yong-Jin
Yun Mi-Young
Kim Dong-Hee
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Abstract
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Antitumor and anti-metastatic effects of mineral powder(MP) were studied. In the present study, MP did not exhibit the any cytotoxic activity against leukemic cells such as L1210 and U937 tumor cell lines in vitro. Also, MP did not exhibit the any cytotoxic activity against solid cells such as A549 and B16-BL6 tumor cell lines in vitro. However, in vivo, MP exhibit a significant antitumor activity in BDF1 mice bearing Lewis lung carcinoma cells(LLC) with inhibition rates of 46 and at 200 and 100 mg/kg/day, respectively. Furthermore, in pulmonary colonization assay, MP exhibit the inhibitory effect of tumor metastasis. From these results, it was concluded that MP had antitumor and anti-metastatic activity suggesting its application for the prevention and treatment of cancer.
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KEYWORD
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Mineral powder, anti-metastatic activity, antitumor activity
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